In a nutshell
- Pytloun Boutique Hotel Prague: A cool design hotel in Prague’s Old Town packed with little luxury touches. Some rooms come with a private terrace or balcony.
- Mosaic House Design Hotel: Seriously creative, decorated with plants throughout, and home to a dedicated spa and wellness area — great for couples.
- MOOo by the Castle: Romantic, charming, and located right next to Prague Castle — one of our top picks for a special stay.
- Nothing quite right yet? We have eight more unique boutique hotels in Prague below — just keep scrolling! Or check out our Where to Stay in Prague guide.
Pytloun Boutique Hotel Prague

The Pytloun Boutique Hotel Prague has made it its mission to anticipate your every wish — a cool, luxurious design hotel that really delivers.
Throughout the hotel you’ll find little touches that make your stay even more enjoyable. We especially love the whirlpool function in the bathtub — such a nice bonus after a day of sightseeing.
Some of the rooms have a terrace or balcony where you can wind down your evening in comfort.
The hotel’s own restaurant serves delicious tapas, and the lobby bar is perfect for working your way through the drinks menu.
Book Pytloun Boutique Hotel Prague
Mosaic House Design Hotel

The Mosaic House Design Hotel earns the “design hotel” label in every sense. The rooms and the entire property are so extraordinarily and creatively decorated that you feel like you’ve stepped inside an artist’s mind — and all at a surprisingly affordable price.
Plants are everywhere throughout the property. The hotel doesn’t call itself the Green Island in the Golden City for nothing.
No island would be complete without a wellness offering, and this unique Prague hotel delivers with private spa and sauna areas. It’s seriously perfect for couples looking for a relaxing, romantic getaway.
Book Mosaic House Design Hotel
Hotel Waldstein

The Hotel Waldstein sits right next to Waldstein Palace on the left bank of the Vltava — a fantastic neighborhood to stay in Prague. Charles Bridge is just a few minutes’ walk away.
This Prague boutique hotel offers a great variety of room options, so whether you’re traveling solo, as a couple, or with the whole family, you’ll find something that fits.
The clever use of indirect lighting gives the Renaissance vaulted cellar an especially warm, cozy feel. In winter, breakfast is complimentary. In summer, you can enjoy it out in the atrium instead.
7 Tales Suites

Stay like you’re living in a fairy tale — that’s exactly what you get at 7 Tales Suites. The design of this one-of-a-kind Prague boutique hotel draws inspiration from well-known Czech fairy tales.
Depending on which of the differently themed rooms you book, you might sleep like the Czech Cinderella or be greeted by a troll in the morning. There’s even a corner in the hallway featuring masks of the individual fairy tale characters — a really fun touch.
The central location near the Old Town Square makes this an ideal base for exploring Prague. And if you’re not in the mood to eat out, the suites’ kitchens mean you can easily cook for yourself.
MOOo by the Castle

As the name suggests, MOOo by the Castle sits right next to Prague Castle. Other major highlights like Charles Bridge are also just a 10- to 20-minute walk away.
The rooms are lovingly and romantically decorated, with little cows hidden here and there on the walls. With kids along, you can have a great time playing “find the cow.”
Even more romantic than the rooms is the charming hotel courtyard, where you can also have breakfast on warmer mornings.
Residence U Černého Orla

Charles Bridge is one of the most iconic Prague attractions. If you want to be just steps from the bridge, your best bet is the Residence U Černého Orla — it’s only a 3-minute walk to Charles Bridge.
This Prague boutique hotel is housed in a beautiful, historic Baroque building with a black eagle on the facade. The name, by the way, translates to “At the Black Eagle.”
Surrounded by embroidered carpets and ornate walls, the rooms will make you feel like you’ve been transported to the Orient.
3 Epoques Aparthotel

The 3 Epoques Aparthotel is located in the oldest building in Prague’s historic center. You’ll be within easy reach of many of the city’s top sights and museums.
The building combines three architectural styles — Romanesque, Gothic, and Renaissance — which is exactly where the name comes from. Pretty cool when you think about it.
The rooms are bright and welcoming, blending rustic and modern furnishings really well. Every apartment also comes with a kitchen.
Romantik Hotel U Raka

Now here’s a boutique hotel of a completely different kind! The Romantik Hotel U Raka is surrounded by lush greenery and even has its own garden. Perfect if you prefer a quieter atmosphere away from the crowds. Prague Castle is just a ten-minute walk away.
This family-run hotel was designed with great attention to detail. There’s even a fireplace where you can warm up on chilly evenings — seriously romantic.
The rooms are rustically yet cozily furnished, with exposed brick and handcrafted pottery that give you a real feel for the house’s traditional roots.
Hotel Republika and Suites

Want a hotel with a serious wellness area? Head straight to Numa Prague Republika.
The spa and wellness center — complete with a whirlpool, Jacuzzi, sauna, and professional massages — leaves absolutely nothing to be desired. The spacious, modern rooms make it super easy to truly switch off.
And if that’s still not enough luxury, you can treat yourself to the President Suite, featuring four bedrooms and a terrace with stunning views over Prague.
The Republika is a great pick for both couples and families.
Hotel Planet Prague

The Hotel Planet Prague occupies the sixth floor of the building — which means two great perks: stunning panoramic views over the city from virtually everywhere in the hotel, plus a beautiful rooftop terrace.
Design-wise, this Prague boutique hotel draws inspiration from outer space. The rooms are done in muted shades of blue with colorful accents and fitting touches like a telescope. It’s genuinely fun.
The hotel is primarily designed with couples in mind, but families are welcome to book as well.
Alcron Hotel

Last but not least: a stunning Art Deco hotel with soaring ceilings right in the city center. The building was constructed in the 1930s and its interiors have been beautifully paired with modern design elements.
With the exception of the Classic and Deluxe rooms, a delicious warm à la carte breakfast is included in the room rate. The fitness center is available to all guests.
Every room at the Almanac X Alcron Prague offers a lovely view over Prague. But the Castle-View Suite and the Presidential Suite offer the best vantage points of all — absolutely worth the upgrade.